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An uncompetitive inhibition pattern was observed for RB and CB as inhibitors when CDNB was used as the variable substrate

Under stress conditions, the glutamatergic system releases unusually high amounts of glutamate into the synapses, which in turn is responsible for neurotoxicity, hyperactivity, and eventually cell death

PubMed: 15070226 Cartilage Protective Effects of AOD 9604 in Transgenic Mice with Accelerated Osteoarthritis animal Wu X, Rasmussen JC, Sawicki G, et al

We examined whether Nrf1 and Nrf2 are important in the transcriptional regulation of the rat GCLC using Nrf1 and Nrf2 knockout (F1 and F2) and wild-type (WT) fibroblasts and found that Nrf1 and Nrf2 are important for the rat GCLC promoter activity despite absence of ARE

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