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Using human liver microsomes, it was also recently reported that sulforaphane metabolites (0-200 M) had little-to-no effect on the activities of CYP1A2, CYP2B6, CYP2D6, and CYP3A4 (23)

Therefore, strategies for mitochondria-mediated ferroptosis in IDD exhibit notable research and application potential (Fig

This work was supported by the NSERC RGPIN-2023-05099 (R.W.)

Anti-interference study NaCl, KCl, CaCl 2 , Na 2 SO 4 , NaNO 3 and NaBr were employed to study the interference of anions, such as Na + , K + , Ca 2+ Cl - , SO 4 2- , NO 3 - and Br - , and the concentration of each anion was set at 10 mM

at high doses , it can become neurotoxic or act as a pro-oxidant