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VPA is used to treat psychiatric disorders and as such there is an association with accidental or deliberate overdose, the incidence of which is increasing [135,136]
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For patients with uncontrolled hypothyroidism, thyroid hormone replacement should be optimized first, as untreated hypothyroidism can affect glucose metabolism and weight management outcomes
Moreover, studies employing magnetic resonance spectroscopy (MRS) have observed alterations in muscle tissue and the brain indicative of mitochondrial dysfunction in long COVID sufferers [38,39,40,41], although data obtained in the heart are inconclusive [33, 42]
Department of Health and Human Services, ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
