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Due to limited clinical efficacy, anti-fibrotic approaches have been superseded by mechanisms that target the underlying driver of NASH pathogenesis, namely steatosis, which drives hepatocyte injury and downstream inflammation and fibrosis
SCD1 regulates the stemness of CSCs through the Wnt/-catenin pathway
Mitochondrial ROS potentiates indirect activation of the AIM2 inflammasome
The process of LR needs to be examined from three dimensions
As Juno orbits around Jupiters poles once every 53 days, it gets within a few thousand miles of the planets cloud tops
