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These genes regulate essential cellular processes, including mitochondrial function, autophagy, lysosomal activity, proteasomal degradation, cellular stress responses, inflammation, and synaptic homeostasis, all of which contribute to the pathogenesis of the disease [24]

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Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer

However, given the lower intracellular GSH:GSSG ratio after IL-13 stimulation, it is difficult to determine the proportionate role that loss of GSH plays in downstream T2-pathway mRNA/protein expression

The defense enzymatic system in neuronal cells is weak where the SOD, catalase, and GPx activities are low compared to other organs