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Description
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Abizaid et al., 2011
Prolonged or excessive use can lead to gastrointestinal issues, kidney damage, and cardiovascular risks
Fundamentally, at the core of cellular antioxidant defense lies an evolutionarily conserved selenocysteine-cysteine redox axis, which serves as the primary defense axis against iron-catalyzed lipid peroxidation cascades and ferroptosis execution [24]
GPX7 has two unique endoplasmic reticulum secreted proteins, the N-terminal endoplasmic reticulum signaling peptides (HGPX7 and MGPX7) and the C-terminal atypical KDEL sequence (endoplasmic reticulum recovery signaling) (Raykhel et al., 2007)
