glutathione platinum resistance Pincer movement”: Reversing cisplatin based on simultaneous depletion and glutathione S-transferases inhibition by redox-responsive degradable organosilica hybrid nanoparticles A platinum(IV) prodrug strategy to
Description
Due to the fact that -glutamylcysteine (product of GCL) is present at exceedingly low concentrations when GS is present, GCL is considered rate limiting (Dalton et al., 2004)

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PMID: 169 HuangKWHsuFFQiuJTChernGJLeeYAChangCCet al

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