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The risk of side effects can be higher in people with certain medical conditions

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In colonic tissue models, gabapentin was associated with: Reduced mast cell density or activation markers Decreased release of inflammatory mediators Improvement in visceral pain signaling These findings suggest gabapentin may exert indirect mast cellregulating effects within colonic tissue in experimental models

2019;7(3) doi: 10.3390/healthcare7030089.89 [DOI] [PMC free article] [PubMed] [Google Scholar] 101.Liu S., Wu H.-J., Zhang Z.-Q., et al
