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GSH is incapable of penetrating cell membranes due to its high hydrophilicity and being negatively charged at physiologic pH

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Cell Death Dis 11(2):144 Yamada N, Karasawa T, Wakiya T, Sadatomo A, Ito H, Kamata R, Watanabe S et al (2020b) Iron overload as a risk factor for hepatic ischemia-reperfusion injury in liver transplantation: potential role of ferroptosis