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And microscopically, he had very dense and extensive tau pathology In a pattern and distribution diagnostic of stage two, CTE is a progressive degenerative disease caused by repetitive head impacts, and although that can include concussions, much more importantly, it includes sub concussive hits

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The change in the surface area of the nisin chains that are exposed to either water or POPE/POPG lipids leads to a change in the number of contacts and hydrogen bonds between water or POPE/POPG molecules with nisin chains