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Description
A B12 deficiency can lead to anemia, which reduces the oxygen-carrying capacity of the blood, resulting in fatigue, weakness, and shortness of breath

Pathophysiology: The Biologic Basis for Disease in Adults and Children
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Moderate levels are found in the periaqueductal gray matter and raphe nuclei, and low concentrations are seen in the hypothalamus, preoptic area, and globus pallidus (Quirion et al., The distribution of KOR demonstrates some of the most striking species differences among the OR types
