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P., Gordon-Larsen, P., Lavie, C

This metabolic switch suppresses neutrophil pulmonary infiltration by downregulating CXCR2 expression and inhibiting NADPH oxidase assembly, reducing bronchoalveolar lavage fluid (BALF) protein extravasation in septic models (Jiao et al., 2023)

An inulin fiber diet promotes type-2 immune responses after spirochete infection in an eosinophil-dependent manner (93)

Mechanistically, these interventions modulate disease processes by restoring microbial balance, increasing SCFA production, and downregulating type 2 inflammatory pathways, including the suppression of IL-5 and IL-13 as well as eosinophilic activity

Changes in Levels of the Antioxidant Glutathione in Brain and Blood Across the Age Span of Healthy Adults: A Systematic Review. NeuroImage: Clinical 40: 103503