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Recently, nuclear factor of activated T cells (NFAT) and Foxp3 levels have been reported to be reduced in Tregs from patients with generalized vitiligo, which may impair Tregs function and decrease IL-10 and cytotoxic T-lymphocyte-associated antigen-4 (CTLA4) levels (7274)
on August 31, 2020
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Therefore, by increasing the intracellular pool of inositol phosphates, myo-ins administration enhances PKC activity and restores the correct retinoic acid signaling, preventing NTDs
