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Experiments using in vivo EXOs therapy have shown little to no harm (Elsharkasy et al., 2020)

Yao H, Li C, He F, Song T, Brosseau JP, Wang H, et al

JMIR Mental Health [Internet]
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[DOI] [PubMed] [Google Scholar] 72.Haddad S., Wang Y., Galy B., Korf-Klingebiel M., Hirsch V., Baru A.M., Rostami F., Reboll M.R., Heineke J., Flgel U., et al

Moreover, calcium-binding proteins play a vital role in modulating oxidative stress and inflammatory responses, two major contributors to neurodegenerative processes [184]
