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The PI3K/mTOR dual inhibitor NVP-BEZ235 stimulates mutant p53 degradation to exert anti-tumor effects on triple-negative breast cancer cells

Although experimental studies have been highly instrumental in shedding novel information on aspects involved in MeHg-induced neurotoxicity, further research on the role of microglial cells and neuroinflammation, as well as potential therapeutic/antidotal strategies is warranted

The combination of antiangiogenic therapy with chemotherapy, targeted therapy, or immunotherapy has emerged as a promising approach for overcoming drug resistance in breast cancer

The measurement of sperm antioxidant indexes T-AOC, CAT, GSH-Px, and NO followed kit instructions and was performed using a microplate reader

This could be at least in part due to direct inhibition of cGMP phosphodiesterase (PDE5) activity, leading to an increase in the half-life of cGMP [170]