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Gut dysbiosis and cardiovascular health: A comprehensive review of mechanisms and therapeutic potential

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Nonetheless, some peptides/proteins have advanced through drug development, as shown in Table 4

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The used methods included high-performance liquid chromatography coupled with mass spectrometry, Alamar Blue assay, real-time qPCR, and the Mito Stress Test of the Seahorse Analyzer (Agilent, Santa Clara, California, USA)

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[ 185 ] The maximum tested concentration of fucoidan, a large hydrophilic polysaccharide of 140 kDa with a measured LogP of 1.49, was 0.08% (w/w)

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Samples may be collected from preclinical pharmacology studies for drug PK analysis comparisons in the disease model if the model allows

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