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10.1136/annrheumdis-2018-213299 Ann Rheum Dis
Deficiency can raise homocysteine and impair methionine recycling
Side effects in trials included water retention, increased appetite, and mild fasting glucose elevation, consistent with sustained GH secretagogue activity
Bottom line: Standard glutathione supplements often break down in the gut
The current studys observation of elevated medium-chain acylcarnitines (C8, C10) contrasts with prior literature, representing a novel finding
