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This is a judgment call that depends on specific circumstances and how questions are phrased

For the research context the article is key for understanding why the amylin + GLP-1 combination makes mechanistic sense

[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Peng C.K., Huang K.L., Wu C.P., Li M.-H., Hu Y.-T., Hsu C.-W., Tsai S.-H., Chu S.-J

The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes
