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Sufenidone (NCT06125327), deupirfenidone (NCT05321420) and yifenidone (NCT05060822) are the pirfenidone analogs that have been chemically modified to improve pharmacokinetics and reduce side effects

7 , 55 Physiological hair graying often follows the three-fifty rule, where about 50% of individuals have at least 50% white hair by age 50

68 Antioxidation Oxidative stress is defined as a relative excess of reactive oxygen species (ROS) and typically accompanies excessive proliferation of tumor cells

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EA at GV20 alleviated cerebral injury by reducing the level of TNF- and IL-1 in the brain, serum, and small intestine