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doi: 10.1016/j.freeradbiomed.2018.01.009

165 The fungal cell wall component -glucan can activate pattern recognition receptors on immune cells, such as dendritic cells and macrophages, triggering an inflammatory response characterized by the release of proinflammatory cytokines (e.g., IL-6 and TNF-)

Nevertheless, experts agreed that patients with a long history of AA should not be precluded from treatment with a JAK inhibitor

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Cyclophosphamide , an alkylating agent, exerts its cytotoxicity by forming DNA cross-links and is used in breast cancer, lymphomas, and autoimmune malignancies