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The observed effect of DPI2 was comparable to that of erastin, indicating that DPI2 might trigger cellular ferroptosis via a mechanism analogous to that employed by erastin ( Sorafenib, a multikinase inhibitor, has gained widespread use in the treatment of clinically advanced hepatocellular carcinoma, offering patients prolonged survival

Rab-mediated cellular trafficking defects are also known to be induced by mutant forms of SOD1, TDP-43, and FUS (Soo et al., 2015

This analysis determines the specific peel combination not the other way around

Such folding behavior of at least the GFP moiety may be supported by the highly reversible nature of its denaturation and renaturation processes around neutral pH, demonstrated by recovery of fluorescence upon various denaturation mechanisms [26]

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