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Fumarate Hydratase deficiency
Use with caution in patients with severe kidney disease or seizure disorders under medical supervision

There is no causal effect on AQP4-IgG-seropositive NMOSD risk (OR = 5.471 10 3 , CI = 1.090 10 6 27.465, P = 0.2798) by circulating L-carnitine
The treatment algorithm incorporating these therapies for mild-to-severe acne vulgaris in patients with SOC is summarized in Figure 1
