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HDAC6 is known for removing acetyl groups from non-histone proteins such as -tubulin, cortactin and heat shock protein 90 (HSP90), which play vital roles in preserving cell structure, movement and response to stress (8-10)

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Prostaglandins have been used topically to stimulate melanogenesis, while Melitane, a biomimetic peptide that activates the melanocortin one receptor, has shown promise in promoting hair pigmentation

However, these notions need to be studied in more detail in the future (Jain et al., 2012)