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MBL and collectins (Collectin-10 and Collectin-11), due to their carbohydrate recognition domain, are part of the superfamily of fibrinogen-like proteins, whereas ficolins have a fibrinogen-like recognition domain and belong to the superfamily of fibrinogen-like proteins

Kansaku K, Itami N, Kawahara-Miki R, Shirasuna K, Kuwayama T, Iwata H

Common causes include: Pernicious anemia, an autoimmune disorder hindering Vitamin B12 absorption Gastrointestinal surgeries, like gastrectomy, impact Vitamin B12 uptake Long-term use of certain medications, such as metformin or proton pump inhibitors Diets lacking in Vitamin B12, often seen in vegans and vegetarians For those without a deficiency, Vitamin B12 injections are not typically recommended, as their body can naturally regulate and excrete excess amounts of the vitamin

To demonstrate scalability, the CBs from large-scale batches 6 and 7 were also run on 20 mL GSH columns, and similar column performance and consistent infectivity yield were achieved at both process scales (Supplementary Figures S8AC)

Helps in energy production and DNA synthesis