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While short-term increases in cortisol support adaptive energy regulation, chronic elevationsespecially from prolonged or frequent fastingmay promote muscle catabolism, reduce metabolic health, and impair insulin sensitivity [44]

Factors such as poor diet, environmental toxins, and chronic stress can further deplete glutathione levels

But does more vitamin C always mean better support

Generally, when the power of ferroptosis-promoting cellular activities markedly outweighs ferroptosis-defending capabilities, cytomembranes tend to rupture upon the sustained stimulation of superfluous lipid peroxides and then, ferroptotic cell death can eventually take place [22, 23]