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Regarding to immune response, oxaliplatin-treated neurons release significant amounts of pro-inflammatory cytokines, mainly TNF- and IL-6, whereas prostaglandin E2 levels were significantly higher in macrophagues exposed to the platinum compound than in control cells
Figure 3 2.4 Molecular regulation of ammonium metabolic reprogramming in tumors Tumor cells exhibit distinct ammonium metabolism compared to normal cells, characterized by aberrant expression and activity of SLC, metabolic enzymes, and signal transduction pathway rewiring
In addition, epithalon delivered by injection may occasionally cause inflammatory reactions surrounding the injection site
