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For psoriasis specifically, topical application has obvious appeal since the condition manifests on the skin surface

Int Rev Cell Mol Biol

Emphasis is placed on the unique biochemical properties, excretion pathways, organ system targets, and immunologic effects of individual toxins

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In this study, we choose the following immune cell marker genes as the label for each cell cluster and use the UMAP feature map and bubble map to show the expression of the marker genes 22 : Naive T (LEF1, CCR7), Effector memory CD8 + T (CD8A), Activated CD4 + T (IL7R), Circulating NKs (FCGR3A, TYROBP), Naive B cell (IGHD, TCL1A), Regulatory T cell (IL2RA), Memory B cell (AIM2, TNFRSF13B), NKs (GZMB, XCL1), Plasma cell (JCHAIN, MZB1), Monocyte (LYZ, S100A9), Proliferating CD4 + T (MKI67, TOP2A), Megakaryocyte (PPBP, PF4), DCs (PLD4, SOX4)