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[DOI] [PMC free article] [PubMed] 166.Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, et al

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Auclair A, Drouin C, Cotecchia S, Glowinski J, Tassin JP

Attention is paid primarily to the attenuation of various intracellular signals in target cells, e.g., rearrangement and disruption of the internalization of the allergen-bridged high-affinity IgE receptor (FcRI), transinhibition or internalization of the FcRI receptor with engagement of the low-affinity inhibitory receptor for the Fc region of immunoglobulin gamma (FcRIIb), synthesis of blocking drug-specific immunoglobulins G4 (IgG4), alteration of signaling pathways in mast cells and/or basophils, and reduced calcium ion (Ca2+) influx into cells (Figure 6) [109,112,113,114]

doi: 10.1016/j.jtos.2023.07.001 299 ChenQWangLWeiYXuXGuoXLiangQ