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The biosynthesis of ether lipids initiates in peroxisomes with two key enzymes glyceronephosphate O-acyltransferase (GNPAT), alkylglycerone phosphate synthetase (AGPS) [105]

found that, as the concentration of gallic acid increased, the upregulation of the gene icaR repressed the synthesis of PIA [76]

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Another study published in the Scandinavian Journal of Medicine & Science in Sports in 2018 found that increasing muscle carnitine during 24 weeks of HIIT (high-intensity interval training) did not enhance muscle metabolic adaptations or performance gains beyond those with HIIT alone
