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PMCID: PMC6770181.

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doi: 10.1038/s41467-017-00369-y

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NAD+ levels go down as you age, which leads to cognitive decline, cancer, metabolic disease, and muscle loss

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The formation of the complex is further stabilized by several interactions between hTrx1 residues 58 hTrx1 to 74 hTrx1 and the helical hTrxR1 residues Glu103 hTrxR1 to Glu122 hTrxR1 (Fig

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