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Dose-response characterisation for each peptide individually before combination studies is important for establishing that the doses used produce submaximal individual effects and allowing detection of additive or synergistic combination responses

It is the imbalance between the oxidants and antioxidants that result in delayed wound healing

In the absence of intracellular nucleophiles such as GSH, this reactive metabolite ( N -acetylbenzoiminoquinone) not only reacts with nucleophilic groups of cellular proteins resulting in direct hepatocellular damage, but also participates in redox cycling, thereby generating reactive O 2 species ( ROS ) and consequent oxidative stress that greatly enhance APAP-induced hepatotoxicity

Inzucchi, S

Wait 10 to 15 seconds for the alcohol to evaporate completely before proceeding