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An alternative approach that has been explored experimentally in the porcine ischemic injury model to limit formation of LA inhibitory fragments while maintaining the ability of LA to induce recovery of barrier function involves addition of small doses of LA over time and suggest that 0.1 M LA applied every 45 min is effective (49)

(2013) Quantification of l-ergothioneine in human plasma and erythrocytes by liquid chromatographytandem mass spectrometry

Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals

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Proposed future directions include advanced nanodelivery systems, eutectic technologies, and precision nutrition strategies, which together could accelerate the translation of these natural compounds from the laboratory to clinical application