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The gut microbiota can maintain epithelial homeostasis to support the development of gutassociated lymphoid tissue (GALT) and also enhances epithelial cytokine production, which regulates the action of T and B lymphocytes, macrophages, and polymorphs, maintains gut barrier integrity, and prevents systemic inflammation (Belkaid and Hand 2014

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: Study Group 4no-treatment control: 3.9%