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For samples for which the peak intensity was lower than the blank threshold, metabolites were annotated as not detected, and the threshold value was imputed for any statistical comparisons to enable an estimate of the fold change as applicable

Dies kann zu einer starken Blutdrucksenkung fhren, begleitet von Symptomen wie Kopfschmerzen und Schwindel

Notably, in vitro studies report that clofazimine also inhibits CYP2C8, CYP2D6, and CYP3A4/5, indicating the likelihood of clinically significant interactions with drugs metabolised by these isoenzymes (Lamprene, 2019

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