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Notably, mitochondrial dysfunction is closely linked to NLRP3 inflammasome activationbone marrow-derived macrophages deficient in Lcn2 exhibit reduced mitochondrial damage, accompanied by diminished NLRP3 activation and decreased IL-1 production [126]

However, carnitine itself does not "burn fat"

To determine if acetylcarnitine could serve as a metabolic intermediate in the generation of acetyl-CoA in the nuclear-cytosolic compartment in DKO cells, we traced palmitate and glucose into acetylcarnitine

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