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A large amount of NADPH generated via the PPP is consumed to synthesize cysteine and GSH [26]
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DOI: 10.1016/j.bpg.2015.04.005 Sollid, L
299 In addition, EZH2 represses AMBRA1 and LC3B , further reducing autophagic flux
Obviously, intravenous administration results in quicker and higher peak levels compared to oral delivery 28
