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Known as the "gamma gap," an increase in total globulin levels can signal a systemic inflammation marker and increase mortality risk, especially from pulmonary causes

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Moreover, poor adherence to the therapeutic indications and the presence of comorbidities are two very frequent factors that can modulate the worsening of symptomatology, leading to its chronicity [29,30,31,32]

Effect of Cannabidiol on Cyclooxygenase Type 1 and 2 Expression and Function in Human Neutrophils