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It works best as part of a comprehensive approach that includes dietary changes, physical activity, and consistent treatment

The impact of endotrophin on the progression of chronic liver disease

acknowledges support from the National Institutes of Health (R01GM151682)

Ongoing and future trials will determine the best antiviral combinations and whether the current seemingly rich pipeline is sufficient for successful treatment of all patients in the face of major challenges, such as HCV diversity, viral resistance, the influence of host genetics, advanced liver disease and other co-morbidities
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