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10) Getting There Quickly and Cost Effectively Creating analytical tools that support the advancement of knowledge can often come about through the integration of existing information and techniques, theoretical and practical, directed toward a desired outcome

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J Clin Invest 2003

Consistent with this notion, our supplementary experiment using a stronger SDS paradigm (5-minute defeat episodes) revealed a stress-intensity-dependent exacerbation of anxiety-like behaviors: WT mice, which showed no anxiety phenotype under the milder SDS condition, developed clear anxiety-like responses when the stress load was increased, whereas KI mice displayed even more pronounced behavioral impairments