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Moreover, Nrf2 inhibited ferroptosis in cancer cells (Fig

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AndaniFMTalebi-GarakaniEAshabiGGanbariradMHashemniaMSharifiMet al

First, a toxic loop involving ferroptosis, -synuclein, and neuromelanin exists in the PD microenvironment, yet this study has not clarified the bidirectional regulation between ferroptosis and -synuclein oligomersspecifically, whether oligomers disrupt LIP homeostasis to trigger ferroptosis, or how lipid peroxidation products from ferroptosis accelerate protein aggregation

Highly active antiretroviral therapy drug combination induces oxidative stress and mitochondrial dysfunction in immortalized human blood-brain barrier endothelial cells