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Description
This model is no exception
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As emphasized, although not specifically investigated in the glaucoma rats, the recently described activation of the Src-Caveolin-1-eNOS pathway [103,104] and interaction with several molecular pathways [103,104,107,108,109,110,111,112,113,114,115] may be important for maintaining vasomotor tone, and thereby essential for prompt therapeutic effect in glaucoma rats

Semaglutide is a synthetic 31-residue GLP-1 receptor agonist with extended plasma half-life, also characterised by Novo Nordisk research through a parallel design strategy: a C18 fatty-diacid acylation that produces albumin binding and a similar seven-day half-life

Some patients stay on a lower maintenance dose long term, which is also a reasonable choice
