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Mechanistic themes seen in preclinical research In animal and mechanistic work, AOD-9604 has been associated with: Increased lipolysis (breaking down stored fat) Reduced lipogenesis (reducing fat storage) Interactions with -adrenergic pathways in adipose tissue have been discussed as part of its lipolytic signaling profile (OUP Academic) In obese animal models, AOD-9604 has shown reductions in body weight and body fat and changes consistent with increased fat mobilization
231,232 Crocetin alone has also demonstrated antithrombotic effects in laboratory and animal studies
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In clinical contexts, AOD 9604 has also been evaluated in obesity-related trials, where ongoing work continues to assess its potential role
