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Theres research showing, quite a few research papers, that aluminum is directly associated with slowing this gene down

High-yield and high-purity isolation of hepatic stellate cells from normal and fibrotic mouse livers

Mol Aspects Med 24:1126

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Several animal studies have demonstrated that BCAAs, particularly leucine, exert significant effects on skeletal muscle protein such as stimulation of muscle protein synthesis also by possible interactions with the innate immune system with resulting modified cytokine expression [33]