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4 Targeting the fibroblast with melanocortin drugs 4.1 The melanocortin system at a glance The peptides adrenocorticotropic hormone (ACTH), -, -, and -melanocyte-stimulating hormones (, , MSH) are the four endogenous melanocortin peptides derived from the enzymatic processing of a larger precursor termed proopiomelanocortin protein (POMC)

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