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Wang Y, Chen F, Le B, Stepp DW, Fulton DJ
Meighan, et al
Several studies have shown that anti-EpCAM antibodies limit therapeutic efficacies as the results of showing dose- and target-dependent in metastatic cancers, short serum half-life, altered EpCAM expression pattern, and differential cleavage and localization of EpICD in cancer cells (Fig
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Nat Rev Drug Discov, 2013