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2 The decrease in enzymatic activity is additive across these polymorphisms

Huynh VA, Takala TM, Murros KE, Diwedi B, Saris PEJ

1 Any underlying cause of deficiency, such as gastrointestinal or pancreatic disease, will also need to be addressed

[ref] A recent study of histamine intolerance patients found that they had a significantly higher abundance of histamine-secreting bacteria[ref] Histamine plus other biogenic amines: The DAO enzyme is also used by the body to break down other biogenic amines, including tyramine, putrescine, cadaverine, spermidine, and spermine

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