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The 5mg vial dosing guide covers practical preparation

This relatively high concentration helps protect the stability of the red blood cell membrane and prevents hemoglobin from being oxidized to methemoglobin, thereby preserving its oxygen-carrying capacity

[PubMed: 16554528] 445

doi: 10.1093/ajcn/85.1.193

While these results may suggest a more frequently displaced window of implantation in the endometrium of older women undergoing IVF with fresh embryo transfer, this study does not separate the contribution of the embryo (which is more likely to be aneuploid in older subjects) from the contribution of the endometrium even though synchrony is a composite of the two