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Hereby, zinc acts in a direct manner by binding reversibly to regulatory sites in signaling proteins, or indirectly by influencing enzymes such as phosphatases which are a component of and regulate signaling pathways [45]

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The PLC-mediated release of inositol trisphosphate, IP 3 (from membrane-associated phosphatidylinositol-4,5-bisphosphate, PIP 2 ), leads to the release of intracellular stores of Ca 2+

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RRID:SCR_016479) unless stated otherwise

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