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Amanitin intoxication: Effects of therapies on clinical outcomesa review of 40 years of reported cases

Chen, C., Fan, P., Xie, X

doi: 10.1016/j.jvs.2010.09.018

Injectable routes carry a particular concern for immunogenicity from peptide aggregation and impurities, and FDA noted the available certificates of analysis for AOD-9604 bulk drug substances did not consistently control for impurities, aggregates, or microbial limits
