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The development of antiviral drugs and basic principles of drug discovery Development of antiviral drugs Approval of idoxuridine (the first approved antiviral drug) In 1963, idoxuridine (Fig
MTHFR is critical to methylation
Establishment of PDXOS model and therapeutic effect evaluation The osteosarcoma patient-derived xenograft animal model (PDX) was established in female BALB/c nude mice

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On the experiment day, all subjects consumed the same breakfast (200 g of steamed rice) 90 min before the exercise session to normalize the effects of a pre-exercise meal
